BACTERIOLOGICAL PROFILE OF CATHETER ASSOCIATED URINARY TRACT INFECTION IN MEDICAL INTENSIVE CARE UNIT

Dr. Swati Sahai, Dr. S. Vasanthi, Dr. D. Agatha

Abstract


Background: Urinary tract infection (UTI) is the most common nosocomial infection among which more than 80% are catheter-associated
(CAUTI)[1]. As compared to patients in non-critical area, those in intensive care unit have more risk of acquiring CAUTI [2,3]. Objective: This study
was conducted to determine the bacteriological prole of catheter associated urinary tract infection in medical intensive care unit (ICU) patients
and perform antibiotic susceptibility pattern of the isolated organisms. The risk factors associated with CAUTI was also determined. Methods: A
total of 100 patients admitted in medical ICU and put on Foley's catheter were included in the study. They were followed up for the development of
symptomatic CAUTI as per CDC guidelines. Urine culture, isolation and identication of organism were done by per standard microbiological
methods. Antibiotic susceptibility testing was done by disc diffusion and MIC method following CLSI guidelines. Results: This study identied 26
CAUTI cases with 40 isolated organisms. Most isolates were from Enterobacteriaceae (34.5%) and non-fermenters (32.5%). Pseudomonas
aeruginosa was the most common (25%), followed by Klebsiella pneumoniae (17.5%), Enterococcus faecalis (15%), Escherichia coli (15%), and
Candida spp. (15%). High resistance was noted among Enterobacteriaceae, with 66.67% ESBL, 22.22% Amp C, 11.11% MBL, and 11.11%
carbapenemase production. One methicillin-resistant Staphylococcus aureus was also isolated. Conclusion: The development of CAUTI is
frequently observed in critically ill patients, with most cases being attributed to Gram-negative organisms. The rise of antimicrobial resistance is a
global concern, with a growing number of multidrug-resistant strains causing CAUTI. To reduce the incidence of drug resistance, the prophylactic
use of antibiotics should be avoided.


Keywords


Catheter associated UTI, nosocomial, ESBL, MBL

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