Dr. Ravindra Ramteke, Dr. Rajendra Madane, Dr. Aparna Kulkarni


Coronary heart disease (CHD) is among the top five causes of morbidity worldwide, and is increasingly becoming common in India as well. Cardiovascular diseases accounts for approximately 12 million deaths annually and is the commonest cause of death globally.(1)  Coronary artery disease (CAD) is a group of disorders which involves thrombotic lesion in coronary artery.  This includes chronic coronary syndrome of chronic stable angina and acute coronary syndrome (ACS) which includes acute myocardial infarction with or without ST-segment elevation (STEMI and NSTEMI) and unstable angina diagnosed on electrocardiogram.(1,2) Diagnosis of such disorders is still a challenge despite the considerable progress in the diagnostic modalities .(1,2)


Coronary heart disease (CHD), Coronary artery disease (CAD), ACS, STEMI and NSTEMI

Full Text:



Shah SN. Anand MP. Billimoria AR, Kamath SA, Karmad DR et al. API textbook of Medicine. 8th edition. New Delhi, 2008:507-26.

Fauci AS, Kasper DL, Longo DL, Braunwald E. Hauser S. et al. Harrison's Principles of Internal Medicine. 7th edition. New Delhi, Mc Graw Hill Medical 2008(2):1514-30.

Cesari F. Marcucci R. Caporale R. et al. Relationship between high platelet turnover and platelet function in high-risk patients with coronary artery disease on dual antiplatelet therapy. ThrombHaemost 2008;99:930-35.

Khandekar MM, Khurana AS, Deshmukh SD, et al. Platelet volume indices in patients with coronary artery disease and acute myocardial infarction: an Indian scenario. J Clin Pathol. 2006;59:146-9.

Corash L. Tan H. Gronick HR. Heterogeneity of human whole blood platelet subpopulations. I. Relationship between buoyant density, cell volume and ultrastructure, Blood. 1977;49(1):71-87.

Thompson CB, Eaton KA, Princiotta SM. et al. Size dependent platelet subpopulation: relationship of platelet volume to ultrastructure, enzymatic activity and function. Br J Haematol 1982:50(3):509-519.

Huo Y. Ley KE Role of platelets in the development of atherosclerosis Trends in Cardiovascular Medicine 2004;14:18-228.

Endler G. Klimesch A. Sunder-Plassmann H. et al. Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. Br J Haematol 2002;117:399-404.

Senaran H. Ileri M, Altinbas A. et al. Thrombopoietin and mean platelet volume in coronary artery disease. ClinCardiol. 2001;24:405.

Biradar S. Kashinakunti S. Manjula R. Platelet volume indices in Acute coronary syndrome, a case control study. International journal of advances medicine.2016;3(2):349-352.

Latger-Cannard V. Hoarau M, Salignac S. Baumgart D et al. Mean platelet volume:Comparison of three analysers towards standardization of platelet morphological phenotype. International Journal of Laboratory Hematology. 2012;34(3):300-310.

Slaaka G. Perkmann T, Haslacher H. Greisenegger S. Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease. Arteriosclerosis, thrombosis and vascular biology. 2011;31(5):1215-1218.

El-Dosouky II, Shehata IE. Value of the Mean Platelet Volume in Evaluation of Patients with Acute Coronary Syndrome. Journal of Medical Diagnostic Methods. 2016;5(1):201.

Patil KS, Karchi SD. A comparative study of platelet indices in acute coronary syndrome. International Journal of Contemporary Medical Research 2017;4(3):657-660.

Malepati B. Hanifah M, Prasath A, Vadlamudi H. Mean platelet volume in acute coronary syndrome. Indian journal of applied research. 2016:6(1):369-371.

Kumar V, Melhotra S. Ahuja Ret RC and Viash AK. Platelet and Acute Coronary Syndrome. J Fam Med. 2016;3(4):1063.

Assiri AS, Jamil AM, Mahfouz AA, Mahmoud AS, Ghallab S. Diagnostic importance of platelet parameters in patients with acute coronary syndrome admitted to a tertiary care hospital in southwest region, Saudi Arabia. J Saudi Heart Assoc. 2012; 24: 17-21.

Dehghani MR, Taghipour-Sani L, Rezaei Y, Rostami R. Diagnostic importance of admission platelet volume indices in patients with acute chest pain suggesting acute coronary syndrome. Indian Heart journal. 2014; 66(6):622-828.


  • There are currently no refbacks.